Singapore Nursing Research Conference

March 22-24, 2021 | Online Event

1 (702) 988-2320

Yue Lu

Renowned Speaker for Nursing Conference 2021- Yue Lu
Yue Lu
Peking University School of Nursing, China
Title : The relationship between serum vitamin D and the muscle fitness in patients receiving maintained haemodialysis


Background: Traditionally, vitamin D is thought to be related to the health of bone and metabolism of calcium and phosphorus. Recently, the effect of extra-bone in vitamin D has become a new research point. Because of renal failure, patients undergoing maintained haemodialysis (MHD) may have a decrease of serum vitamin D. Muscle fitness, which include the normal level of muscle mass, muscle strength and physical activity, has also become a hot topic in MHD patients. And the previous study of ours found a decrease of appendicular muscle mass in MHD patients, which was also an important predictive factor of death of these patients.
Aim: To explore the relationship between vitamin D and muscle fitness of maintained haemodialysis patients.
Methods: A cross-sectional study. The serum vitamin D was tested by the method of electrochemiluminescence. Muscle mass was measured by bioelectrical impedance technology and presented as the appendicular muscle mass. The muscle strength was measured by the Jamar digital hand dynamometer to test the grip strength. The physical activity was measured through 4-m usual walking speed test to assess the gait speed.
Results: Of the 155 MHD patients, twelve patients (7.7%) had a sufficient level of serum vitamin D, thirty-seven patients (23.9%) had an insufficient level and one hundred and six patients (68.4%) had a level of vitamin D under 20ng/ml which was defined as deficiency. According to the standard of European Working Group on Sarcopenia in Older People (PWGSOP), taking the muscle fitness of healthy Chinese people as the reference, the percentage of decreased appendicular muscle mass, grip strength and gait speed of the MHD patients was 41.9%, 20.6% and 32.9%, respectively. The correlation analysis showed that the level of serum vitamin D was positively correlated to appendicular muscle mass (r=0.199, p=0.013), grip strength (r=0.311, p<0.0001) and the gait speed (r=0.251, p=0.002).
Conclusion: The deficiency of vitamin D is quite common in Chinese MHD patients. And they also suffer a decrease of muscle fitness at the same time. Increasing the level of serum vitamin D might be a new and efficient way to improve the muscle fitness of MHD patients, which may, in turn, have some help in improving the quality of life of MHD patients.


Ms. Yue Lu graduated from Peking University Health Science Center and got her bachelor’s degree in 2000. Then after working as a physician for 4 years, she quit her job and got her master’s degree in neuroscience in 2007 in Peking University. From 2017, she began her doctoral degree study in nursing. Her special interest is management of chronic kidney disease patients and the patients suffering chronic pain. Ms. Lu has published 2 SCI papers, both of which are the journal of Q1. She is also the reviewer of the journal of Pain Management Nursing.


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