Title: Effect of low-dose heparinized saline (LDHS) on arterial line patency in patients with severe covid-19 disease
Abstract:
Purpose: This research was to find an approach to reduce or prevent obstruction and prolong the useful life of the arterial pressure measurement tape of COVID-19 patients by studying the efficacy of low dose heparin in 0.9% normal saline (LDHS) on the use of arterial pressure transducers in patients with COVID-19 in intensive care units.
Design: Randomized controlled trial.
Methods: The participants consisted of 61 critically ill COVID-19 patients aged over 18 years admitted to the ICU were randomly divided into experimental groups (n=31) and control groups (n=30). The experimental group (Group A) received 2 units of heparin per 1 ml of 0.9% normal saline. The control group (Group B) received 0.9% NSS as usual. Both groups received intravenous pressure at 400 mm Hg. Comparative analysis of the proportion of the Arterial line that is usable and the complications between groups were tested using Pearson's chi-square. Line viability was compared using Kaplan-Meier survival analysis and the log rank test.
Main findings: Using 2 units of heparin in 1 ml of 0.9 %NSS to lubricate the arterial pressure line was as effective as using 0.9% NSS in preventing blockage of the arterial pressure line. Average use was 6.7 days vs. 5.2 days (p-value = 0.66), with no differences in baseline characteristics between groups such as age (67.8 vs 63.7, p = 0.33), BMI (22.9 vs. 23.2, p =0.55) had underlying disease (71% vs. 83.3% p, =0.55).
Conclusion and Recommendations: The study findings can be incorporated into clinical practice guidelines to guide healthcare providers in optimal treatment of arterial lines in critically ill patients. On the basis of this research, low-dose heparin in 0.9% normal saline solution (NSS) and maintaining a pressure of 400 mmHg could be recommended. Healthcare professionals, particularly nurses who often manage these lines, should be educated and trained on the updated practice guidelines. This includes regular evaluation of the function, position and site of the arterial line, ensuring the integrity of the dressing, and maintaining the pressure of the pressure bag at 400mmHg.
Audience Take Away Notes:
1. The findings of this research will enable viewers to understand the reasons behind the malfunction of arterial lines used for blood pressure measurement
2. This study presents guidelines for the continuous and prolonged care of arterial lines in patients, consolidating them into a preliminary care flow chart for managing patients with arterial lines. It also includes guidelines for addressing issues such as blockages or failure to measure blood pressure accurately within the arterial lines
3. This approach is suitable for nurses responsible for managing patients with arterial lines. It provides an easily understandable framework for resolving arising issues and preventing potential risks, especially benefiting less-experienced nurses in caring for patients with arterial lines
