V-care development: Capturing and analyzing immune related adverse events

Title: V-care development: Capturing and analyzing immune related adverse events

Abstract:

Introduction: Immunotherapy revolutionizes the treatment of many different types of cancers. But it is associated with a myriad of Immune-related adverse events (irAEs). Patient-reported outcomes (PROs) are recognized as valuable tools for continuously collecting patient-centred data and are frequently used in oncology trials. However, a few studies researching ePRO follow-up approach on patients treated with immunotherapy that may reflect a lack of support services for this population.
Methods: The team co-developed a digital platform (V-Care) using ePROs for a new follow-up pathway for cancer patients receiving immunotherapy. We used multiple methods to functionalize the first three phases of the CeHRes roadmap. These phases were not performed sequentially but were interwoven all over the developmental process.
Results: The development of the application was categorized into two phases “user interface” (UI) and “user experience” (UX) designs. In the first phase, the pages of the application were segmented into
general categories. Based on the received feedback from all stakeholders, the application was modified. In phase two, the mock-up pages were sent to the Figma website. Also, Android Package Kit (APK) of the application was installed and tested several times on the mobile phone to proactively detect and fix any errors. After solving some technical issues and adjusting the errors on the android version to provide a better experience for the users, the iOS version of this application was developed.
Conclusion: The findings from our project can be used to investigate whether symptoms collected by the ePRO tools on cancer patients being treated with ICIs follow symptoms reported in clinical trials and if there are linked to specific symptoms that do occur.

Biography:

Dr. Moradian has worked in a variety of clinical settings before consolidating his nursing career within the areas of Nursing Research and Oncology. He graduated from the University of Manchester’s Nursing PhD program in the UK. He was engaged as a postdoctoral research fellow in the Department of Supportive Care of the Princess Margaret Cancer Centre (PM) and the Faculty of Nursing at the University of Toronto. He is working as an assistant professor at York University. Dr. Moradian’s research program focuses on reducing the burden of complex cancer symptoms and improving the quality of self-management support in the cancer system. His research has explored novel methods and innovative techniques to find more effective ways in controlling and managing complex symptoms in cancer patients. Most of his recent studies and contributions focus on interventions using e-technology to empower patients to manage their symptoms and improve patient-professional interactions.